Key result
Individualized transfer functions provided a modest but significant advantage over nonindividualized approaches for estimating central aortic blood pressure waveforms in swine subjects.
Why the study?
Do individualized transfer functions improve the accuracy of central aortic blood pressure waveform estimation compared to nonindividualized functions in a swine model?
Do individualized transfer functions improve the accuracy of central aortic blood pressure waveform estimation compared to nonindividualized functions in a swine model?
Fully individualized transfer functions are recommended for estimating central aortic blood pressure under nonnominal physiologic conditions, while nonindividualized functions may suffice under nominal conditions.
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Animal data indicate modest gains from individualized transfer functions; leaves open human validation before any clinical consideration.
Jin‐Oh Hahn (2013) studied this question. Individualized transfer functions (ITF 1, ITF 2, ITF 3) vs. Fully nonindividualized transfer function (NITF) was evaluated on Root-mean-squared waveform error and absolute errors associated with systolic and pulse pressures. Individualized transfer functions provided a modest but significant advantage over nonindividualized approaches for estimating central aortic blood pressure waveforms in swine subjects.
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