February 1, 1989Proceedings of the National Academy of SciencesOpen Access

Trigeminovascular fibers increase blood flow in cortical gray matter by axon reflex-like mechanisms during acute severe hypertension or seizures.

View Full Paper

Ask AI

Bookmark

Population

Cats

Comparison

Unilateral trigeminal ganglionectomy or… vs Sham operation

Design

Preclinical

Authors

DSDamianos E. SakasNational and Kapodistrian University of Athens MMMichael A. MoskowitzUniversity of Iowa EWE. P. WeiUniversity of Hong Kong

Discussion

Member takes

Implication

Highlights trigeminovascular mediation of CBF adaptation in animals; hypothesis-generating for human cerebrovascular regulation.

Structured PICO

Population

Cats (n=27 total: 13 unilateral trigeminal ganglionectomy, 6 sham operation, 8 trigeminal root section/rhizotomy)

Intervention

Unilateral trigeminal ganglionectomy or trigeminal root section (rhizotomy)

Comparator

Sham operation

Outcome

Cerebral blood flow in 10 symmetrical brain regions measured using radiolabeled microspheressurrogate

Trigeminovascular fibers mediate cerebral blood flow adaptations during severe hypertension and seizures via local axon reflex-like mechanisms.

Cite This Study

Sakas et al. (1989) studied this question.

synapsesocial.com/papers/6a7074e984cc45bb7bdfc56c https://doi.org/10.1073/pnas.86.4.1401

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Trigeminovascular fibers increase blood flow in cortical gray matter by axon reflex-like mechanisms during acute severe hypertension or seizures.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Trigeminovascular fibers increase blood flow in cortical gray matter by axon reflex-like mechanisms during acute severe hypertension or seizures.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider