Key result
Wavelet-based filtering best preserves ischemic ECG morphology, achieving ~0.99 correlation with clean signals.
Why the study?
Do baseline wander removal techniques improve the preservation of ST changes in simulated ischemic ECGs compared to unfiltered signals?
Do baseline wander removal techniques improve the preservation of ST changes in simulated ischemic ECGs compared to unfiltered signals?
Butterworth high-pass filtering is recommended for baseline wander removal in ischemic ECGs as it balances computational efficiency with accurate preservation of ST segment changes.
Answers are grounded in this paper and cite their sources.
Wavelet methods may aid ischemic ECG research; leaves open clinical translation without human validation.
The most important ECG marker for the diagnosis of ischemia or infarction is a change in the ST segment. Baseline wander is a typical artifact that corrupts the recorded ECG and can hinder the correct diagnosis of such diseases. For the purpose of finding the best suited filter for the removal of baseline wander, the ground truth about the ST change prior to the corrupting artifact and the subsequent filtering process is needed. In order to create the desired reference, we used a large simulation study that allowed us to represent the ischemic heart at a multiscale level from the cardiac myocyte to the surface ECG. We also created a realistic model of baseline wander to evaluate five filtering techniques commonly used in literature. In the simulation study, we included a total of 5.5 million signals coming from 765 electrophysiological setups. We found that the best performing method was the wavelet-based baseline cancellation. However, for medical applications, the Butterworth high-pass filter is the better choice because it is computationally cheap and almost as accurate. Even though all methods modify the ST segment up to some extent, they were all proved to be better than leaving baseline wander unfiltered.
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Lenis et al. (2017) studied Myocardial ischemia with ECG ST-segment changes corrupted by baseline wander. Wavelet-based baseline cancellation (and four other baseline wander removal filters: Butterworth high-pass, moving median, cubic spline, and wavelet high-pass) vs. Unfiltered baseline-corrupted ECG signals and alternative filtering techniques was evaluated on ECG morphology preservation (correlation coefficient between original and reconstructed signal) and ST-segment K-point (KP) deviation (p=<10^-6). Wavelet-based baseline cancellation best preserved ischemic ECG morphology, while Butterworth filtering was fastest.
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