Key result
This focused review discusses potential predictors of PVC-induced cardiomyopathy, including PVC frequency and characteristics, as well as proposed mechanisms for its development.
Why the study?
A subset of individuals with PVCs develop cardiomyopathy that can dramatically improve with PVC treatment, highlighting the need to review predictors and proposed mechanisms of PVC-induced cardiomyopathy.
Identifying and treating PVC-induced cardiomyopathy can lead to dramatic improvement in cardiac function.
Supports PVC suppression in unexplained cardiomyopathy; leaves open optimal predictors and thresholds for intervention.
Premature ventricular complexes (PVCs) are encountered frequently in clinical practice. While PVCs may have various causes, a small number of individuals with PVCs develop cardiomyopathy in the absence of other potential etiologies. When correctly identified, patients with PVC-incuded cardiomyopathy can have dramatic improvement of their cardiomyopathy with treatment of their PVCs. In this focused review, we discuss potential predictors of PVC-induced cardiomyopathy, including PVC frequency, PVC characteristics, and modifiable patient risk factors. We also review some proposed mechanisms of PVC-induced cardiomyopathy and conclude with future directions for research and clinical practice.
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Pundi et al. (2023) conducted a review in Premature ventricular contraction induced cardiomyopathy. This focused review discusses potential predictors of PVC-induced cardiomyopathy, including PVC frequency and characteristics, as well as proposed mechanisms for its development.
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