Key result
Shenfu injection plus Western medicine was the most effective intervention for dilated cardiomyopathy, ranking highest for clinical effective rate (OR 0.21; 95% CI 0.12-0.34).
Why the study?
The comparative efficacy of six tonic Chinese herbal injections versus Western medicine for the deteriorating state associated with dilated cardiomyopathy required evaluation.
Do tonic Chinese herbal injections added to Western medicine improve clinical and functional outcomes in patients with dilated cardiomyopathy?
Meta-Analysis (n=2,970)
Do tonic Chinese herbal injections added to Western medicine improve clinical and functional outcomes in patients with dilated cardiomyopathy?
Odds Ratio: 0.21 (95% CI 0.12–0.34)
In a network meta-analysis, Shenfu injection combined with Western medicine emerged as the most effective Chinese herbal injection strategy for improving clinical efficacy and cardiac function in dilated cardiomyopathy.
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Supports adjunctive Shenfu injection for dilated cardiomyopathy; extends network meta-analysis evidence for integrative therapies.
Wang et al. (2021) conducted a meta-analysis in Dilated cardiomyopathy (n=2,970). Tonic Chinese herbal injections (e.g., Shenfu injection) plus Western medicine vs. Western medicine alone or other herbal injections was evaluated on Clinical effective rate (OR 0.21, 95% CI 0.12-0.34). Shenfu injection plus Western medicine was the most effective intervention for dilated cardiomyopathy, ranking highest for clinical effective rate (OR 0.21; 95% CI 0.12-0.34).
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