Why the study?
The positive effects of combining traditional Chinese medicine injections with Western medicine treatment on HFrEF and HFmrEF required more comprehensive and systematic evidence.
Does the combination of traditional Chinese medicine injections with Western medicine treatment improve clinical effectiveness and surrogate markers in patients with HFrEF and HFmrEF compared to Western medicine alone?
Population
Patients with HFrEF or HFmrEF across 101 RCTs
Comparison
Five traditional Chinese medicine injections combined with Western medicine treatment vs Western medicine treatment alone
Design
Bayesian network meta-analysis of RCTs
Authors
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TCMIs plus WMT improve efficacy over WMT alone in HFrEF/HFmrEF; reinforces Chinese RCT data but leaves open need for multicenter validation.
Does the combination of traditional Chinese medicine injections with Western medicine treatment improve clinical effectiveness and surrogate markers in patients with HFrEF and HFmrEF compared to Western medicine alone?
Traditional Chinese medicine injections combined with standard Western medicine may improve clinical effectiveness and surrogate markers in HFrEF and HFmrEF, though evidence is limited to Chinese populations.
Zheng et al. (2023) studied this question.
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