Key result
Carotid artery intima-media thickness is elevated in hypertensive heart disease and predicts cardiovascular events, but its addition to traditional risk scores provides negligible net reclassification improvement.
Why the study?
Does carotid artery intima-media thickness (cIMT) assessment improve prognostic utility and risk reclassification in patients with hypertensive heart disease?
Does carotid artery intima-media thickness (cIMT) assessment improve prognostic utility and risk reclassification in patients with hypertensive heart disease?
While cIMT is a recognized surrogate marker for target organ damage in hypertension, its routine clinical use is limited by measurement variability and negligible added prognostic value over traditional risk scores.
Cautions against routine addition to risk scores in hypertensive heart disease; leaves open targeted validation in prospective cohorts.
Sustained by its relative ease of assessment, carotid artery intima-media thickness (cIMT) has emerged as an important surrogate marker of target organ damage in hypertensive heart disease over the last three decades. However, the prognostic utility of cIMT in hypertensive heart disease differs depending on its application. This review outlines cIMT and its prognostic utility among patients with hypertensive heart disease. It provides an overview of limitations of cIMT and areas for future research.
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Costan G. Magnussen (2017) conducted a review in Hypertensive heart disease. Carotid artery intima-media thickness (cIMT) was evaluated. Carotid artery intima-media thickness is elevated in hypertensive heart disease and predicts cardiovascular events, but its addition to traditional risk scores provides negligible net reclassification improvement.
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