Why the study?
Does preoperative propranolol therapy increase the risk of hypertension following coronary artery bypass surgery?
Population
52 patients undergoing coronary artery bypass surgery over a 9-month period
Comparison
Preoperative propranolol therapy vs No preoperative propranolol therapy
Design
Cohort
Follow-up
Early postoperative period
Authors
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Preoperative propranolol was associated with post-CABG hypertension; this observational link leaves open causality and needs prospective confirmation.
Does preoperative propranolol therapy increase the risk of hypertension following coronary artery bypass surgery?
Preoperative propranolol administration is strongly associated with the development of hypertension following coronary artery bypass surgery, which appears to be driven by an increase in systemic vascular resistance rather than renin-angiotensin mediation.
Whelton et al. (1980) studied this question.
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