Population
Embryonic and neonatal mice, including a PlexinD1 mutant mouse model
Design
Preclinical
Authors
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Supports advanced phenotyping in mouse models; leaves open translation to clinical congenital heart disease assessment.
Micro-CT with iodine staining provides a low-cost, low-toxicity method for high-resolution 3D phenotyping of cardiovascular development and congenital defects in mouse models.
Degenhardt et al. (2010) studied this question.
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