Why the study?
Does propranolol provide better cost-effectiveness compared to other antihypertensive monotherapies in adults aged 35-64 with mild to moderate hypertension?
Population
Persons aged 35 through 64 years with diastolic blood pressure of 95 mm Hg or greater and no known coronary…
Comparison
Various antihypertensive monotherapies vs Comparative analysis among the different…
Design
Other
Follow-up
20 years (simulated)
Authors
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Should not yet change prescribing based on modeling alone; extends cost-effectiveness simulations but requires prospective validation.
Does propranolol provide better cost-effectiveness compared to other antihypertensive monotherapies in adults aged 35-64 with mild to moderate hypertension?
Propranolol and hydrochlorothiazide appear to be the most cost-effective initial monotherapies for mild to moderate hypertension based on long-term simulation modeling.
J. T. Edelson (1990) studied this question.
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