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January 1, 2009Physiological ResearchOpen Access

Mechanisms of chronic heart failure development in end-stage renal disease patients on chronic hemodialysis

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Population

End-stage renal disease (ESRD) patients on chronic hemodialysis

Design

Review

Authors

JMJan MalíkCharles UniversityVTVladimír TukaCharles UniversityMMMagdaléna MokrejšováUniversity Hospital Hradec Králové

Discussion

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Implication

Supports holistic evaluation of heart failure in dialysis patients; leaves open mechanism-specific intervention trials.

Structured PICO

P
Population
End-stage renal disease (ESRD) patients on chronic hemodialysis

This review highlights the complex, multifactorial mechanisms—including volume overload, hypertension, anemia, and vascular access flow—that drive the high incidence of congestive heart failure in ESRD patients on chronic hemodialysis.

Limitations

  • The steady state of CHF in ESRD patients does not exist due to volume load changes between dialyses

Cite This Study

Malík et al. (2009) studied this question.

synapsesocial.com/papers/6a7080d26c240de38cdbd57fhttps://doi.org/10.33549/physiolres.931614

Topics

Heart failureHFrEF treatment
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE CLINICAL EPIDEMIOLOGY OF CARDIOVASCULAR DISEASES IN CHRONIC KIDNEY DISEASE: Cardiovascular Disease in Chronic Renal Failure: Pathophysiologic Aspects2003 · 308 citations
  2. 2Effect of Preload Reduction by Hemodialysis on Conventional and Novel Echocardiographic Parameters of Left Ventricular Structure and Function2007 · 29 citations
  3. 3Effect of hemodialysis on blood volume distribution and cardiac output.1981 · 68 citations
  4. 4Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension*2005 · 755 citations
  5. 5Salt – A Potential ‘Uremic Toxin’?2005 · 61 citations