Why the study?
Does altering the timing of atrial systole affect hemodynamics in heart block dog preparations?
Population
Heart block dog preparations with ganglionic blockade and vagotomy
Comparison
Altering the timing of atrial systole relative… vs Properly timed atrial systole or absence of…
Design
Preclinical
Authors
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AV dyssynchrony may impair hemodynamics in heart block; confirms atrial timing importance in dogs but leaves open human translation.
Does altering the timing of atrial systole affect hemodynamics in heart block dog preparations?
Properly timed atrial activity is crucial for enhancing ventricular filling and preclosing the atrioventricular valve to prevent mitral regurgitation.
Skinner et al. (1963) studied this question.
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