The authors discuss the growing recognition of organic lesions, such as primary aldosteronism, as underlying causes of hypertension.
SINCE the advent of more refined technics in the diagnosis of hypertension of renal and adrenal origin, and indeed since the realization that such conditions actually exist, there has been widespread renewed interest in this field, particularly in the possible relation of these types of hypertension to so-called essential hypertension and consequent explanation of the presently unknown etiologic factors involved.There is a growing body of opinion that an organic lesion will be found, possibly in the adrenal glands or kidney, to account for the hypertensive state observed in the majority of patients suffering from hypertensive cardiovascular disease. We believe . . .
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Smithwick et al. (1962) studied this question.
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