Why the study?
Does head-up tilt testing induce vasovagal syncope more frequently in subjects with blood/injury phobia compared to healthy controls?
Population
22 subjects total: 11 with a history of syncope or presyncope only in response to a blood or injury stimulus…
Comparison
45 minutes of head-up tilt to 70 degrees… vs Healthy matched controls undergoing the same…
Design
Case-control
Follow-up
45 minutes
Authors
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Heightened syncope risk during orthostasis in blood phobia warrants awareness; supports autonomic dysregulation hypothesis but leaves causal confirmation open.
Does head-up tilt testing induce vasovagal syncope more frequently in subjects with blood/injury phobia compared to healthy controls?
Subjects with blood/injury phobia exhibit an underlying autonomic dysregulation that predisposes them to neurally mediated syncope during orthostatic stress, even without exposure to the phobic stimulus.
Accurso et al. (2001) studied this question.
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