Population
Feline calicivirus (FCV)-infected cells and in vitro translation systems
Comparison
Proteinase K treatment to remove VPg, addition… vs Untreated FCV RNA and cellular RNA
Design
Preclinical
Authors
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VPg-dependent FCV translation at high K+ extends viral initiation models; leaves open relevance to other caliciviruses or antivirals.
FCV RNA is linked to a 15 kDa VPg protein and is translated by a cap-independent mechanism that functions at high K+ concentrations.
Herbert et al. (1997) studied this question.
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