Why the study?
Does angiotensin II affect renal artery resistance in vitro, and is this effect mediated by alpha-2 adrenergic receptors?
Does angiotensin II affect renal artery resistance in vitro, and is this effect mediated by alpha-2 adrenergic receptors?
Angiotensin II potentiates norepinephrine-induced constriction in rat renal arteries in vitro via an alpha-2 adrenergic receptor-mediated mechanism.
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May enhance norepinephrine constriction via alpha-2 receptors in rat renal arteries; hypothesis-generating for combined blockade in hypertension.
Ajikobi et al. (1994) studied this question.
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