November 1, 2000Hypertension

Plasma Hydrogen Peroxide Production in Human Essential Hypertension

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Population

Family-based cohort consisting of family members ascertained through probands with essential hypertension.

Design

Cohort

Authors

FLFred LacySouthern University and Agricultural and Mechanical College MKMala T. KailasamUniversity of California, San Diego DODaniel T. O’ConnorNova Southeastern University

Discussion

Member takes

Implication

Should not yet alter clinical assessment in hypertension; leaves open whether genetically influenced hydrogen peroxide drives cardiorenal decline.

Structured PICO

Population

Family-based cohort consisting of family members (n=236) ascertained through probands (n=57) with essential hypertension.

Outcome

Heritability of hydrogen peroxide production and its correlation with cardiac contractility and renal functionsurrogate

Hydrogen peroxide production has a substantial heritable component and correlates negatively with cardiac and renal function in patients with essential hypertension.

Cite This Study

Lacy et al. (2000) studied this question.

synapsesocial.com/papers/6a709a60b27f158178276ecc https://doi.org/10.1161/01.hyp.36.5.878

Topics

Hypertension management

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Implication

Should not yet alter clinical assessment in hypertension; leaves open whether genetically influenced hydrogen peroxide drives cardiorenal decline.

Plasma Hydrogen Peroxide Production in Human Essential Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Plasma Hydrogen Peroxide Production in Human Essential Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider