Why the study?
Are reactive oxygen species and nitric oxide levels altered in human essential hypertension compared to normal controls?
Are reactive oxygen species and nitric oxide levels altered in human essential hypertension compared to normal controls?
Essential hypertension is associated with increased free radical generation and decreased nitric oxide and antioxidants, which normalize with antihypertensive therapy.
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Reversible oxidative imbalance tracks with BP control in essential hypertension; leaves open whether antioxidant targeting improves outcomes.
Kumar et al. (1993) studied this question.
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