What question did this study set out to answer?

To assess the efficacy and utility of saline contrast intracardiac echocardiography compared to standard pulmonary vein angiography for guiding cryoballoon occlusion during pulmonary vein isolation.

November 1, 2012Indian Pacing and Electrophysiology JournalOpen Access

Usefulness of Contrast Intracardiac Echocardiography in Performing Pulmonary Vein Balloon Occlusion during Cryo-ablation for Atrial Fibrillation

View Full Paper

Ask AI

Bookmark

Why the study?

Does contrast intracardiac echocardiography with saline contrast reduce procedural time and contrast use compared to fluoroscopy with iodinated contrast in patients undergoing cryoballoon ablation for paroxysmal atrial fibrillation?

Key Points

To assess the efficacy and utility of saline contrast intracardiac echocardiography compared to standard pulmonary vein angiography for guiding cryoballoon occlusion during pulmonary vein isolation.
Randomized trial of 30 consecutive patients with paroxysmal atrial fibrillation assigned to fluoroscopy plus color-flow Doppler with iodinated contrast (Group 1, n = 15) or intracardiac echocardiography plus color-flow Doppler with saline contrast (Group 2, n = 15).
Assessed 338 occlusions across 107 pulmonary veins, analyzing diagnostic agreement of occlusion, isolation success rates, total procedure time, fluoroscopy exposure, and contrast volume.
Pulmonary vein isolation achieved with ≤ 2 double cryofreezes reached 89% in group 1 versus 91% in group 2 (p=n.s.), with high diagnostic agreement between saline contrast echocardiography and angiography.
Saline contrast guidance significantly shortened total procedure duration (127 ± 16 vs. 152 ± 19 minutes; p<0.05) and fluoroscopy time (30 ± 12 vs. 43 ± 9 minutes; p<0.05).
Iodinated contrast volume was significantly lower in the saline contrast echocardiography group compared to standard angiography (88 ± 26 vs. 190 ± 47 mL; p<0.05).

Structured PICO

Population

30 consecutive patients with paroxysmal atrial fibrillation undergoing cryoballoon ablation

Intervention

Contrast intracardiac echocardiography plus color-flow Doppler using saline contrast for guidance of cryoballoon ablation

Comparator

Fluoroscopy plus color-flow Doppler using an iodinated medium for guidance of cryoballoon ablation

Outcome

Assessment of pulmonary vein occlusion and pulmonary vein isolation (PVI) ratesurrogate

Intracardiac saline echocontrastography is an effective alternative to pulmonary vein angiography for guiding cryoballoon ablation, significantly reducing procedural time, fluoroscopy exposure, and iodinated contrast use.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Supports saline intracardiac echocardiography to cut radiation and contrast in cryoballoon PVI; extends RCT evidence for imaging alternatives in AF ablation.

Cite This Study

Catanzariti et al. (2012) studied this question.

synapsesocial.com/papers/6a709b4431a3df824328dc42 https://doi.org/10.1016/s0972-6292(16)30563-0

View Full Paper

Ask AI

Bookmark

Implication

Supports saline intracardiac echocardiography to cut radiation and contrast in cryoballoon PVI; extends RCT evidence for imaging alternatives in AF ablation.

Usefulness of Contrast Intracardiac Echocardiography in Performing Pulmonary Vein Balloon Occlusion during Cryo-ablation for Atrial Fibrillation

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Usefulness of Contrast Intracardiac Echocardiography in Performing Pulmonary Vein Balloon Occlusion during Cryo-ablation for Atrial Fibrillation

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider