Why the study?
Does 24-hour ambulatory blood pressure monitoring improve the assessment of blood pressure variability in patients with orthostatic hypotension compared to one-time measurement?
Does 24-hour ambulatory blood pressure monitoring improve the assessment of blood pressure variability in patients with orthostatic hypotension compared to one-time measurement?
24-hour ambulatory blood pressure monitoring is highlighted as necessary to adequately assess the high blood pressure variability in patients with orthostatic hypotension.
One-time BP readings may miss high variability in orthostatic hypotension; leaves open whether routine ambulatory monitoring improves assessment or outcomes.
The presence of orthostatic hypotension has been shown to be a significant, independent predictor of all-cause mortality. Systolic and diastolic orthostatic hypotension, reversal of the circadian pattern, and postprandial hypotension are some of the hemodynamic factors that may contribute to the increased mortality seen in patients with orthostatic hypotension. The high variability of blood pressure in orthostatic hypotension cannot usually be adequately assessed by a one-time measurement. In this group of patients, 24-hour ambulatory.
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Ejaz et al. (2007) studied this question.
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