Why the study?
Do enalapril, atenolol, or verapamil reduce cardiac arrhythmias and transient myocardial ischemia compared to hydrochlorothiazide in hypertensive patients with LVH?
Do enalapril, atenolol, or verapamil reduce cardiac arrhythmias and transient myocardial ischemia compared to hydrochlorothiazide in hypertensive patients with LVH?
Antihypertensive therapy with enalapril, atenolol, or verapamil, but not hydrochlorothiazide, reduces left ventricular mass, cardiac arrhythmias, and transient myocardial ischemia in hypertensive patients with LVH.
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Supports preferring enalapril, atenolol, or verapamil over HCTZ in LVH hypertension; extends LV mass regression data to arrhythmic and ischemic endpoints.
Salvatore Novo (2001) studied this question.
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