Key result
Antihypertensive therapy with ramipril and felodipine reduced left ventricular mass index (142 to 123 g/m2; P<0.01) but did not lead to a sustained reduction in total ventricular ectopics.
Why the study?
Does antihypertensive therapy with ramipril and felodipine reduce cardiac arrhythmias in hypertensive subjects?
Observational (n=26)
Does antihypertensive therapy with ramipril and felodipine reduce cardiac arrhythmias in hypertensive subjects?
Regression of left ventricular hypertrophy achieved with ramipril and felodipine does not lead to a sustained reduction in ventricular arrhythmias.
No takes yet. Share an insight, caveat, or question.
LVH regression should not yet guide arrhythmia management; leaves open dedicated trials of antihypertensive effects on ventricular ectopy.
Jamil Mayet (1997) conducted an observational in Hypertension with left ventricular hypertrophy (n=26). Ramipril with felodipine if required vs. Baseline was evaluated on Ventricular ectopic total. Antihypertensive therapy with ramipril and felodipine reduced left ventricular mass index (142 to 123 g/m2; P<0.01) but did not lead to a sustained reduction in total ventricular ectopics.
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