Why the study?
Does long-term warfarin therapy reduce mortality and recurrent MI in subgroups of patients after acute myocardial infarction?
Population
1214 patients after acute myocardial infarction (MI)
Design
Cohort
Follow-up
mean 37 months
Authors
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Does not support long-term warfarin in these subgroups; leaves open need for RCTs on post-MI anticoagulation.
Does long-term warfarin therapy reduce mortality and recurrent MI in subgroups of patients after acute myocardial infarction?
Long-term warfarin therapy for secondary prophylaxis after acute MI may lack beneficial effects in patients with prior MI or diabetes mellitus.
Pål Smith (1992) studied this question.
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