Population
Smooth muscle strips isolated from the hog common carotid artery
Comparison
10 microM histamine stimulation vs Other vasoactive agents and various…
Design
Preclinical
Authors
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Histamine may trigger single-unit rhythmicity in large-artery smooth muscle; extends multi-unit models but leaves clinical relevance untested.
Hog carotid artery smooth muscle, typically considered multi-unit, can exhibit single-unit behavior with rhythmic contractions specifically induced by histamine via H1 receptors.
Stein et al. (1984) studied this question.
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