Why the study?
Do restricted rules for QT alerting improve the identification of patients at risk of developing Torsades de Pointes compared to old rules in inpatients?
Population
49 inpatients with overridden drug-drug interaction alerts regarding QT prolongation and an ECG recorded…
Comparison
Restricted rules for QT alerting vs Old rules for QT alerting
Design
Cohort
Follow-up
1 month
Authors
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QT-alert restriction may miss half of inpatients at TdP risk without PPV gain; leaves open whether refined rules can safely curb fatigue.
Do restricted rules for QT alerting improve the identification of patients at risk of developing Torsades de Pointes compared to old rules in inpatients?
Restricting QT-alert rules to reduce alert fatigue resulted in poorer identification of patients at risk for Torsades de Pointes without improving the positive predictive value of the alerts.
Sijs et al. (2009) studied this question.
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