Why the study?
Does bedtime administration of hypertension medications reduce cardiovascular morbidity and mortality compared to morning administration in hypertensive patients?
Population
Hypertensive patients
Comparison
Bedtime administration of ≥1 conventional… vs Traditional approach of scheduling all…
Design
Review
Follow-up
5.6-yr median follow-up (for the MAPEC study)
Authors
Loading...
May support bedtime dosing for BP profiles; hypothesis-generating for CVD outcomes and should not yet change practice.
Does bedtime administration of hypertension medications reduce cardiovascular morbidity and mortality compared to morning administration in hypertensive patients?
Switching at least one hypertension medication from morning to evening administration improves 24-hour blood pressure profiles and reduces cardiovascular risk.
Portaluppi et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: