Why the study?
Do patients with congestive heart failure exhibit altered circadian rhythms of blood pressure and atrial natriuretic peptide compared to normal subjects?
Do patients with congestive heart failure exhibit altered circadian rhythms of blood pressure and atrial natriuretic peptide compared to normal subjects?
Patients with congestive heart failure lose the normal circadian rhythms of both blood pressure and atrial natriuretic peptide, supporting a causal relationship between the two.
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Altered ANP and BP rhythms in CHF warrant no practice change; hypothesis-generating for causality and rhythm-targeted interventions.
Portaluppi et al. (1991) studied this question.
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