Why the study?
Is there a circadian rhythm of ANF plasma concentrations or a difference in ANF levels between patients with mild essential hypertension and healthy subjects?
Population
22 subjects total: 10 patients with mild/moderate essential hypertension and 12 healthy control subjects.
Design
Case-control
Authors
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ANF shows no circadian rhythm or difference in mild hypertension; hypothesis-generating for its role in blood pressure regulation.
Is there a circadian rhythm of ANF plasma concentrations or a difference in ANF levels between patients with mild essential hypertension and healthy subjects?
There appears to be no significant circadian rhythm of ANF plasma concentrations or difference in baseline ANF levels between patients with mild essential hypertension and healthy subjects.
Scalzi et al. (1991) studied this question.
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