Key result
Among 100 patients with essential hypertension, 70% had ANP plasma concentrations within the normal range of healthy controls, with 52% falling in the lower third or below the normal range.
Population
100 patients aged 19 to 78 years with essential hypertension
Design
Cross-sectional
Authors
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Should not change ANP testing in hypertension care; hypothesis-generating for reduced ANP secretion in pathogenesis.
Cross-Sectional (n=100)
Diminished secretion of ANP may contribute to elevated blood pressure in patients with mild to moderate essential hypertension.
Talartschik et al. (1990) conducted a cross-sectional in Essential hypertension (n=100). Essential hypertension vs. Healthy controls was evaluated on ANP plasma concentrations. Among 100 patients with essential hypertension, 70% had ANP plasma concentrations within the normal range of healthy controls, with 52% falling in the lower third or below the normal range.
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