Why the study?
Do plasma ANP levels correlate with left ventricular and left atrial structural abnormalities in patients with essential hypertension?
Population
67 subjects, comprising 36 patients with untreated essential hypertension and 31 normotensive controls.
Design
Cross-sectional
Authors
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ANP may mark LV remodeling in hypertension; hypothesis-generating and should not yet change practice.
Do plasma ANP levels correlate with left ventricular and left atrial structural abnormalities in patients with essential hypertension?
Plasma ANP levels are elevated in essential hypertension and correlate with left ventricular and left atrial structural abnormalities, suggesting a role of cardiac hypertrophy in ANP secretion.
Wambach et al. (1988) studied this question.
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