What does this research mean for the field?

Plasma BNP levels, but not ANP levels, are significantly elevated in hypertensive patients with left ventricular hypertrophy, suggesting BNP is a useful biomarker for early LVH detection. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2000Sunhwan'giOpen Access

Plasma Concentration of Atrial and Brain Natriuretic Peptides in the Patients with Essential Hypertension

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Why the study?

Do plasma ANP and BNP levels correlate with left ventricular hypertrophy in patients with essential hypertension?

Population

Patients with essential hypertension and normotensive subjects

Comparison

Measurement of plasma ANP and BNP levels and… vs Normotensive subjects

Design

Cross-sectional

Authors

SHSeok Jae HwangGyeongsang National University HKHeung Sun KangAsan Medical Center HLHwae Young LewUniversity of Seoul

Discussion

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Implication

BNP elevation was associated with LVH in hypertension; hypothesis-generating for biomarker screening, needing prospective validation before clinical use.

Structured PICO

Do plasma ANP and BNP levels correlate with left ventricular hypertrophy in patients with essential hypertension?

Population

Patients with essential hypertension and normotensive subjects

Intervention

Measurement of plasma ANP and BNP levels and echocardiographic assessment of left ventricular mass index (LVMI)

Comparator

Normotensive subjects

Outcome

Relationship between plasma ANP/BNP levels and the degree of left ventricular hypertrophy (LVH)surrogate

Plasma BNP levels are significantly elevated in hypertensive patients with left ventricular hypertrophy, suggesting its potential utility as a biomarker for early detection of LVH.

Cite This Study

Hwang et al. (2000) studied this question.

synapsesocial.com/papers/6a1bec0626cb5670aa9d1d62 https://doi.org/10.4070/kcj.2000.30.7.847

Topics

Echocardiography Hypertension management

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Implication

BNP elevation was associated with LVH in hypertension; hypothesis-generating for biomarker screening, needing prospective validation before clinical use.

Plasma Concentration of Atrial and Brain Natriuretic Peptides in the Patients with Essential Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Plasma Concentration of Atrial and Brain Natriuretic Peptides in the Patients with Essential Hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider