Population
8 normal subjects (aged 23-35 years) on a fixed 120 mmol Na+ diet
Follow-up
24 hours
Authors
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ANH nocturnal peak may inform chronotherapy trials; leaves open clinical relevance and requires prospective validation.
Atrial natriuretic hormone displays a diurnal rhythm with a peak at 22:00 h, providing physiological evidence of a reciprocal relationship with plasma renin activity.
McCance et al. (1989) studied this question.
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