May 1, 1990Acta Physiologica Scandinavica

Atrial natriuretic peptide, renin activity, aldosterone, urine volume and electrolytes during a 24‐h sleep‐wake cycle in man

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Population

6 healthy male subjects

Follow-up

24 hours

Authors

JLJuhani LeppäluotoHeart Failure / Cardiomyopathy HRHeikki RuskoahoHeart Failure & Transplant

Discussion

Member takes

Implication

ANP diurnal patterns should not yet guide clinical sampling; leaves open RAAS interactions in cardiovascular disease.

Structured PICO

Population

6 healthy male subjects

Intervention

Observation over a 24-hour sleep-wake period with blood sampling and vital sign recording every 4 hours

Outcome

Diurnal variation in plasma ANP concentrations and its relation to renin activity, aldosterone, urine volume and electrolytessurrogate

Plasma ANP exhibits diurnal variation with a nadir at 04:00 h, likely related to diminished atrial distension during sleep, and does not appear to affect renin or aldosterone secretion in a normal sleep-wake cycle.

Cite This Study

Leppäluoto et al. (1990) studied this question.

synapsesocial.com/papers/6a701f773ce530166bc2bcd4 https://doi.org/10.1111/j.1748-1716.1990.tb08896.x

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Atrial natriuretic peptide, renin activity, aldosterone, urine volume and electrolytes during a 24‐h sleep‐wake cycle in man

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Atrial natriuretic peptide, renin activity, aldosterone, urine volume and electrolytes during a 24‐h sleep‐wake cycle in man

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider