Why the study?
Can early 123I-iobenguane (MIBG) myocardial scintigraphy predict short-term left ventricular functional recovery in a post-MI patient?
Can early 123I-iobenguane (MIBG) myocardial scintigraphy predict short-term left ventricular functional recovery in a post-MI patient?
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Early MIBG myocardial scintigraphy may help predict the absence of left ventricular functional recovery in post-MI patients, potentially guiding early ICD implantation decisions.
(123)I-iobenguane myocardial scintigraphy (MIBG) has been shown to be a predictor of sudden cardiac mortality in patients with heart failure. One patient with recent anterior myocardial infarction (MI) treated with coronary angioplasty and having left ventricular ejection fraction (LVEF) of 30% underwent early MIBG myocardial scintigraphy/tetrofosmin single-photon emission computed tomography (SPECT) in order to help evaluate his eligibility for implantable cardioverter defibrillator (ICD). The late heart/mediastinum (H/M) ratio was calculated to be 1.32% and the washout rate was 1%. At 40-day follow-up after angioplasty, LVEF proved to be 32%, New York Heart Association (NYHA) class was still II-III, and an ICD was placed in order to reduce mortality from ventricular arrhythmias. MIBG myocardial scintigraphy might be a promising method for evaluating left ventricular recovery in post-MI patients.
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Feola et al. (2015) studied this question.
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