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January 1, 2019Clinical Medicine Insights CardiologyOpen Access

Serum Soluble ST2 and Adverse Left Ventricular Remodeling in Patients With ST-Segment Elevation Myocardial Infarction

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Why the study?

The study was conducted to evaluate the dynamics of serum sST2 and NT-proBNP levels and their relationship with adverse left ventricular remodeling through 6 months in STEMI patients.

Population

31 STEMI patients undergoing PCI within 24 hours of MI onset

Design

Cohort study

Follow-up

6 months

Authors

МКМ. А. КерчеваRussian Academy of SciencesTRT. R. RyabovaRussian Academy of SciencesАГА. М. ГусаковаRussian Academy of Sciences

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Implication

May aid post-STEMI LVR risk stratification; leaves open larger prospective validation before clinical use.

Structured PICO

P
Population
31 patients with primary myocardial infarction with ST-segment elevation (STEMI), median age 58 years, who underwent percutaneous coronary intervention (PCI) during the first 24 hours of MI onset.
O
Outcome
Development of adverse left ventricular remodeling (LVR) through 6 monthssurrogate

Elevated serum levels of sST2 by day 7 after STEMI are associated with the development of adverse left ventricular remodeling at 6 months.

Cite This Study

Керчева et al. (2019) studied this question.

synapsesocial.com/papers/6a70b88eb27f158178277cb2https://doi.org/10.1177/1179546819842804
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Also Consider

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  1. 1Improved early risk stratification of patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention using a combination of serum soluble ST2 and NT-proBNP2017 · 39 citations
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  3. 3Comparison Between Soluble ST2 and High-Sensitivity Troponin I in Predicting Short-Term Mortality for Patients Presenting to the Emergency Department With Chest Pain2016 · 27 citations
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