June 23, 2005Journal of Cardiovascular Electrophysiology
Determinants of Recurrent Ventricular Arrhythmia or Death in 300 Consecutive Patients with Ischemic Heart Disease Who Experienced Aborted Sudden Death: Data from the Leiden Out‐of‐Hospital Cardiac Arrest Study
Why the study?
What are the clinical predictors of recurrent ventricular arrhythmia or death in patients with ischemic heart disease who survived sudden cardiac arrest?
Population
300 consecutive patients with ischemic heart disease who survived an episode of sudden cardiac arrest
Design
Cohort
Follow-up
mean 30 +/- 21 months
Authors
Discussion
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Member takes
Implication
May guide risk stratification in ischemic SCA survivors; hypothesis-generating and requires prospective validation before practice change.
Structured PICO
What are the clinical predictors of recurrent ventricular arrhythmia or death in patients with ischemic heart disease who survived sudden cardiac arrest?
P
Population
300 consecutive patients with ischemic heart disease (IHD) who survived an episode of sudden cardiac arrest (SCA)
I
Intervention
Clinical characteristics and treatments including beta-blockers, amiodarone, and coronary revascularization
O
Outcome
Composite of recurrent ventricular arrhythmia and all-cause mortalitycomposite
In survivors of sudden cardiac arrest with ischemic heart disease, beta-blocker use and coronary revascularization are associated with a decreased risk of recurrent ventricular arrhythmias or death.
Cite This Study
Kiès et al. (2005) studied this question.