Modulation by prostaglandin synthesis inhibitors of the action of exogenous angiotensin II on glomerular ultrafiltration in the rat.

27 plasma volume-expanded Munich-Wistar rats

Angiotensin II (A II) infusion with inhibition of prostaglandin (PG) synthesis

Angiotensin II infusion alone, prostaglandin synthesis inhibition alone, and vehicle infusion alone

Determinants of glomerular ultrafiltration (single nephron GFR, total GFR, glomerular plasma flow rate, ultrafiltration coefficient, transcapillary hydraulic pressure difference, afferent and efferent arteriolar resistances)surrogate