Exercise-induced modulation of cardiac lipid content in healthy lean young men

11 healthy lean, untrained young men, mean age 25.4 ± 1.1 years, BMI 23.6 ± 0.8 kg/m2. Excluded if unstable weight (>3 kg change in preceding 6 months) or participating in competitive sports.

2-hour cycling protocol at 50% of maximal power output performed in a fasted state (ingesting water only) to create a state of high plasma fatty acid concentrations.

The same 2-hour cycling protocol at 50% of maximal power output performed while ingesting glucose (1.4 g/kg bodyweight initial bolus followed by 0.35 g/kg at intervals) to create a state of low plasma fatty acid concentrations.

Cardiac lipid content measured by proton magnetic resonance spectroscopy (1H-MRS) at baseline, directly after exercise, and 4 hours post-exercise.surrogate