Why the study?
Does [Dmt(1)]DALDA protect against ischemia-reperfusion-induced myocardial stunning in buffer-perfused hearts?
Does [Dmt(1)]DALDA protect against ischemia-reperfusion-induced myocardial stunning in buffer-perfused hearts?
The opioid peptide analgesic [Dmt(1)]DALDA protects against ischemia-reperfusion-induced myocardial stunning, suggesting potential utility during cardiac interventions or myocardial ischemia.
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Should not yet alter clinical management of ischemia-reperfusion; hypothesis-generating for [Dmt(1)]DALDA superiority over morphine in cardioprotection.
Wu et al. (2002) studied this question.
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