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February 1, 2005Echocardiography

Effects of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy on Doppler Tei Index: A Midterm Follow‐Up

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Why the study?

Does alcohol septal ablation improve Doppler Tei index and myocardial performance in patients with symptomatic hypertrophic obstructive cardiomyopathy?

Population

27 consecutive patients with symptomatic hypertrophic obstructive cardiomyopathy, mean age 53 +/- 13 years.

Design

Cohort

Follow-up

12 months

Authors

JVJosef VeselkaŠPŠárka ProcházkováIBIngrid Bolomová‐Homolová

Discussion

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Overview

Supports enhanced myocardial performance after alcohol septal ablation in HOCM; hypothesis-generating and requires randomized confirmation before practice change.

Key Points

  • This study aims to assess midterm changes in the Doppler Tei index after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy.
  • Twenty-seven consecutive patients with symptomatic HOCM underwent alcohol septal ablation.
  • Echocardiographic data were collected at baseline, 6 months, and 12 months after the procedure.
  • Key parameters tracked included Doppler Tei index, isovolumic relaxation time, and LV ejection fraction.
  • Doppler Tei index decreased from 0.67 to 0.55 (P<0.01).
  • Isovolumic contraction time reduced from 74 ms to 48 ms (P<0.01).
  • Ejection fraction decreased from 78% to 73% (P<0.01), with significant symptomatic improvement noted.

Structured PICO

Does alcohol septal ablation improve Doppler Tei index and myocardial performance in patients with symptomatic hypertrophic obstructive cardiomyopathy?

P
Population
27 consecutive patients with symptomatic hypertrophic obstructive cardiomyopathy (HOCM), mean age 53 +/- 13 years.
I
Intervention
Alcohol septal ablation (PTSMA)
O
Outcome
Midterm changes of Doppler Tei index (TI) at 6 and 12 monthssurrogate

Alcohol septal ablation significantly improves left ventricular myocardial performance as measured by the Doppler Tei index, alongside symptomatic and hemodynamic improvements in patients with HOCM.

Cite This Study

Veselka et al. (2005) studied this question.

synapsesocial.com/papers/6a70c19ee5469ee92be16fe5https://doi.org/10.1111/j.0742-2822.2005.03148.x
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