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Early basal/bolus insulin without oral agents is advocated for managing type 2 diabetes.
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Most patients with type 2 diabetes ultimately need insulin therapy. This paper presents the case for starting insulin therapy sooner rather than later, preferably without oral drugs and in a "basal/bolus" regimen consisting of a daily dose of a long-acting insulin for basal coverage plus preprandial doses of a short-acting insulin.
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Pasquale Palumbo (2004) studied this question. Early initiation of basal/bolus insulin therapy without oral drugs is advocated for managing patients with type 2 diabetes.
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