Why the study?
Evidence needed to be summarized regarding the perioperative management of patients receiving long-term antiplatelet therapy who require elective surgery or procedures to support guideline development.
Does perioperative continuation or bridging of antiplatelet therapy affect major bleeding and thromboembolism in patients receiving long-term antiplatelet therapy undergoing elective surgery?
Population
Patients receiving long-term antiplatelet therapy requiring elective surgery or procedures
Comparison
Different perioperative antiplatelet interruption, continuation, or bridging strategies
Design
Systematic review and meta-analysis
Authors
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Informs perioperative antiplatelet decisions for elective surgery; extends and updates prior ACCP recommendations with systematic evidence.
Does perioperative continuation or bridging of antiplatelet therapy affect major bleeding and thromboembolism in patients receiving long-term antiplatelet therapy undergoing elective surgery?
Perioperative aspirin continuation increases major bleeding but reduces thromboembolism, while LMWH bridging increases bleeding risk.
Shah et al. (2022) studied this question.
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