Why the study?
Does overexpression of specific heat shock proteins protect microtubular integrity during simulated ischemia in rat neonatal cardiac myocytes?
Population
Rat neonatal cardiac myocytes
Comparison
Overexpression of specific heat shock proteins… vs Uninfected myocytes and myocytes infected with a…
Design
Preclinical
Follow-up
14 h
Authors
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Constitutive Hsp70 or αB-crystallin overexpression may preserve microtubular integrity in ischemic myocytes; hypothesis-generating for selective HSP cardioprotection.
Does overexpression of specific heat shock proteins protect microtubular integrity during simulated ischemia in rat neonatal cardiac myocytes?
Overexpression of constitutive Hsp70 and alphaB-crystallin protects microtubular integrity during simulated ischemia in cardiac myocytes, highlighting specific mechanisms of HSP-mediated cardioprotection.
Bluhm et al. (1998) studied this question.
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