Why the study?
CMR reliably estimates post-STEMI outcomes but is expensive and limited in availability, prompting evaluation of widely available TTE strain parameters as surrogates for CMR-measured parameters.
Do transthoracic echocardiography strain parameters correlate with cardiac magnetic resonance-measured infarct size and area at risk in patients with ST-elevation myocardial infarction?
Population
70 STEMI patients with high quality CMR and TTE data
Comparison
TTE strain parameters vs CMR-measured variables
Design
Prospective controlled trial sub-study
Follow-up
4 ± 2 days
Authors
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TTE strain parameters correlate with post-STEMI CMR infarct measures; leaves open their validation as accessible surrogates in future studies.
Do transthoracic echocardiography strain parameters correlate with cardiac magnetic resonance-measured infarct size and area at risk in patients with ST-elevation myocardial infarction?
Transthoracic echocardiography strain parameters, particularly global longitudinal strain and longitudinal peak strain, correlate significantly with CMR-measured infarct size and area at risk, suggesting their potential utility as surrogate endpoints in STEMI clinical trials.
Dannenberg et al. (2021) studied this question.
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