Why the study?
Does previous gestational diabetes mellitus impair vascular function in women prior to the development of hyperglycemia?
Population
17 women with previous gestational diabetes mellitus and normal glucose tolerance, matched with normal…
Comparison
Previous gestational diabetes mellitus (exposure) vs Normal controls matched for body mass index…
Design
Case-control
Authors
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Impaired microvascular hyperaemia associated with prior GDM despite normoglycemia; hypothesis-generating for early vascular changes before hyperglycemia.
Does previous gestational diabetes mellitus impair vascular function in women prior to the development of hyperglycemia?
Women with previous gestational diabetes exhibit impaired microvascular maximum hyperaemia despite normal glucose tolerance, suggesting early vascular dysfunction predating type 2 diabetes.
Hannemann et al. (2002) studied this question.
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