Why the study?
Does nebivolol 5 mg once daily improve blood pressure control and tolerability compared to nifedipine retard 20 mg twice daily in patients with essential hypertension?
Population
Patients with essential hypertension
Comparison
Nebivolol 5 mg oral once daily vs Nifedipine retard 20 mg oral twice daily
Design
RCT, Randomized, Double-blind
Authors
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Supports nebivolol for faster initial BP control in essential hypertension; confirms long-term equivalence to nifedipine retard without orthostasis.
Does nebivolol 5 mg once daily improve blood pressure control and tolerability compared to nifedipine retard 20 mg twice daily in patients with essential hypertension?
Nebivolol 5 mg once daily is as effective as nifedipine retard 20 mg twice daily for long-term blood pressure control in essential hypertension, but offers better tolerability.
Nueten et al. (1998) studied this question.
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