Why the study?
Do captopril and nadolol have differential effects on blood pressure and heart rate during exercise in patients with mild to moderate hypertension?
Do captopril and nadolol have differential effects on blood pressure and heart rate during exercise in patients with mild to moderate hypertension?
Despite similar resting blood pressure control, nadolol provides more pronounced systolic blood pressure and heart rate lowering during exercise compared to captopril in patients with mild to moderate hypertension.
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Nadolol may provide greater exercise SBP control than captopril in hypertension; leaves open outcome implications and requires prospective trials.
Kostis et al. (1992) studied this question.
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