Transmissibility and Persistence of Oral Polio Vaccine Viruses: Implications for the Global Poliomyelitis Eradication Initiative

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Population

Populations involved in household and community transmission studies and mass-vaccination experiences…

Design

Review

Authors

Discussion

Persistence risks warrant inclusion in global OPV cessation planning; leaves open optimal surveillance durations and modeling needs.

Population

Populations involved in household and community transmission studies and mass-vaccination experiences regarding oral polio vaccine (OPV)

Intervention

Oral polio vaccine (OPV) vaccination and its cessation

Outcome

Transmissibility and persistence of OPV viruses

The potential for OPV viruses to persist and revert to neurovirulence must be considered when planning the cessation of OPV vaccination globally.

Fine et al. (1999) studied this question.

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