Why the study?
Does coronary artery bypass grafting compared to percutaneous coronary intervention improve outcomes in octogenarians with coronary artery disease?
Does coronary artery bypass grafting compared to percutaneous coronary intervention improve outcomes in octogenarians with coronary artery disease?
CABG and PCI should be considered complementary procedures in octogenarians, with CABG favored for complex coronary disease and PCI for those with higher surgical risk or less severe lesions.
Answers are grounded in this paper and cite their sources.
May favor CABG over PCI in high-risk octogenarians; leaves open need for randomized confirmation.
PURPOSE OF REVIEW: The aim of this study was to review recent literature reporting the results of coronary revascularization by percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in patients older than 80 years. RECENT FINDINGS: The review of recent studies on octogenarians demonstrates a surgical CABG advantage in the case of patients with increasing baseline coronary risk, such as severe multivessel disease, chronic total occlusions, and left ventricular dysfunction. PCI seems to be more appropriate for less severe degree and distribution of coronary lesions, and for subgroups of patients with higher surgical risk, such as acute coronary syndromes, reoperations, malignancy, dementia, poor mobility, frailty, and serious comorbidities contraindicating extracorporeal circulation. SUMMARY: It is not the case that CABG is indicated only when there are contraindications to PCI. CABG confers more benefit than PCI in patients with increasing baseline cardiac risk, in the absence of serious systemic diseases that can reasonably reduce their life expectancy.CABG and PCI, with proper selection, should be considered complementary rather than competitive procedures in the therapy of octogenarians affected by coronary artery disease.
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Francesco Nicolini (2015) studied this question.
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