Why the study?
Impaired awareness of hypoglycaemia affects approximately 25% of people with type 1 diabetes, and this proof-of-concept study examined whether a single episode of high-intensity training could act as a dishabituating stimulus to amplify counterregulatory responses to subsequent hypoglycaemia.
Does a single episode of high intensity training improve adrenaline response to subsequent hypoglycaemia in adults with type 1 diabetes and impaired awareness of hypoglycaemia?
Population
People with type 1 diabetes and impaired awareness of hypoglycaemia
Comparison
A single episode of high intensity training vs rest
Design
Randomised crossover proof-of-concept study
Authors
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Supports habituation as mechanism of IAH in type 1 diabetes; leaves open whether targeted reversal reduces severe hypoglycaemia.
Does a single episode of high intensity training improve adrenaline response to subsequent hypoglycaemia in adults with type 1 diabetes and impaired awareness of hypoglycaemia?
A single episode of high-intensity exercise partially restores counterregulatory hormonal and symptomatic responses to hypoglycaemia in patients with type 1 diabetes and impaired awareness.
Farrell et al. (2020) studied this question.
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